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 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Clinical Medicine and Pharmacology</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Clinical Medicine and Pharmacology</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Клиническая медицина и фармакология</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2409-3750</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">124443</article-id>
   <article-id pub-id-type="doi">10.12737/2409-3750-2026-12-1-40-44</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>Клинические наблюдения</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>clinical observations</subject>
    </subj-group>
    <subj-group>
     <subject>Клинические наблюдения</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">Clinical observation of a patient with polymorbidity: type 2 diabetes mellitus, osteoarthritis, arterial hypertension, and osteoporosis with a compression fracture of the spine</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Клиническое наблюдение пациентки с полиморбидностью: сахарный диабет 2 типа, остеоартрит, артериальная гипертензия и остеопороз с компрессионным переломом позвоночника</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Царев</surname>
       <given-names>Н. Н.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Carev</surname>
       <given-names>N. N.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Тульский государственный университет</institution>
    </aff>
    <aff>
     <institution xml:lang="en">Tula State University</institution>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2026-05-26T11:19:13+03:00">
    <day>26</day>
    <month>05</month>
    <year>2026</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-05-26T11:19:13+03:00">
    <day>26</day>
    <month>05</month>
    <year>2026</year>
   </pub-date>
   <volume>12</volume>
   <issue>1</issue>
   <fpage>40</fpage>
   <lpage>44</lpage>
   <history>
    <date date-type="received" iso-8601-date="2026-05-26T00:00:00+03:00">
     <day>26</day>
     <month>05</month>
     <year>2026</year>
    </date>
   </history>
   <self-uri xlink:href="https://zh-szf.ru/en/nauka/article/124443/view">https://zh-szf.ru/en/nauka/article/124443/view</self-uri>
   <abstract xml:lang="ru">
    <p>В статье представлен клинический случай пациентки 68 лет с полиморбидным профилем, включающим сахарный диабет 2 типа в стадии субкомпенсации с дистальной полинейропатией, постменопаузальный остеопороз, остеоартрит коленных суставов и артериальную гипертензию с признаками поражения органов-мишеней. Обращение было вызвано развитием острого болевого синдрома в спине на фоне минимальной травмы. При обследовании верифицирован компрессионный перелом тела Th12 позвонка на фоне остеопороза. Описан комплексный междисциплинарный подход к ведению пациентки, включающий коррекцию сахароснижающей и антигипертензивной терапии, инициацию специфической антиостеопоротической терапии и поэтапную восстановительную программу лечебной физкультуры. Особое внимание уделено роли контролируемого увеличения двигательной активности как центрального элемента, позволившего разорвать порочный круг «боль-гиподинамия-прогрессирование заболеваний». Рассмотрены диагностические сложности и недостатки ранее оказанной помощи.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>The article presents a clinical case of a 68-year-old patient with a polymorbid profile, including type 2 diabetes mellitus in the stage of subcompensation with distal polyneuropathy, postmenopausal osteoporosis, osteoarthritis of the knee joints, and arterial hypertension with signs of target organ damage. The referral was caused by the development of acute back pain syndrome against the background of minimal trauma. At the examination, a compression fracture of the body of Th12 vertebra against the background of osteoporosis was verified. A comprehensive interdisciplinary approach to patient management is described, including the correction of antidiabetic and antihypertensive therapy, the initiation of specific anti-osteoporotic therapy, and a step-by-step rehabilitation program of physical therapy. Special attention is paid to the role of controlled increase in physical activity as a central element that allowed breaking the vicious circle of &quot;pain-hypodynamia-progression of diseases.&quot; Diagnostic difficulties and shortcomings of previously provided care are considered.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>полиморбидность</kwd>
    <kwd>сахарный диабет 2 типа</kwd>
    <kwd>остеопороз</kwd>
    <kwd>компрессионный перелом позвоночника</kwd>
    <kwd>артериальная гипертензия</kwd>
    <kwd>лечебная физкультура.</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>polymorbidity</kwd>
    <kwd>type 2 diabetes mellitus</kwd>
    <kwd>osteoporosis</kwd>
    <kwd>spinal compression fracture</kwd>
    <kwd>arterial hypertension</kwd>
    <kwd>therapeutic physical training.</kwd>
   </kwd-group>
  </article-meta>
 </front>
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