PATHOMORPHOLOGICAL CHANGES IN LIVER OF WHITE MICE AT EXPERIMENTAL PLAGUE INFECTION CAUSED BY YERSINIA PESTIS OF DIFFERENT PLASMID COMPOSITION

Dubrovina Valentina; Starovoitova Tatyana; Mukhturgin Gennadiy; Vityazeva Svetlana; Kotlov Mikhail; Balakhonov Sergey

doi:doi:10.12737/article_59a614fbe83145.69615594

Home / Journals / Acta biomedica scientifica / Volume 2 Issue 2 / PATHOMORPHOLOGICAL CHANGES IN LIVER OF WHITE MICE AT EXPERIMENTAL PLAGUE INFECTION CAUSED BY YERSINIA PESTIS OF DIFFERENT PLASMID COMPOSITION

PATHOMORPHOLOGICAL CHANGES IN LIVER OF WHITE MICE AT EXPERIMENTAL PLAGUE INFECTION CAUSED BY YERSINIA PESTIS OF DIFFERENT PLASMID COMPOSITION

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PATHOMORPHOLOGICAL CHANGES IN LIVER OF WHITE MICE AT EXPERIMENTAL PLAGUE INFECTION CAUSED BY YERSINIA PESTIS OF DIFFERENT PLASMID COMPOSITION

Journal: ACTA BIOMEDICA SCIENTIFICA Volume 2 № 2 , 2017

Rubrics: EXPERIMENTAL STUDY IN BIOLOGY AND MEDICINE

UDK 61 Медицина. Охрана здоровья

Dubrovina Valentina ¹

Starovoitova Tatyana ²

Mukhturgin Gennadiy ³

Vityazeva Svetlana ⁴

Kotlov Mikhail ⁵

Balakhonov Sergey ⁶

Author and publication information

Authors:

1. Irkutsk Antiplague Research Institute of Siberia and Far East (Laboratory of Pathophysiology, Head)

Irkutsk, Irkutsk region, Russian Federation

2. Irkutsk Antiplague Research Institute of Siberia and Far East (Laboratory of Pathophysiology, Research Officer)

Irkutsk, Irkutsk region, Russian Federation

3. Irkutsk Antiplague Research Institute of Siberia and Far East (Laboratory of Experimental Animals, Junior Research Officer)

Irkutsk, Irkutsk region, Russian Federation

4. Irkutsk Antiplague Research Institute of Siberia and Far East (Department of Plague Microbiology, Senior Research Officer)

Irkutsk, Irkutsk region, Russian Federation

5. Irkutsk Antiplague Research Institute of Siberia and Far East (Laboratory of Pathophysiology, Research Assistant)

Irkutsk, Irkutsk region, Russian Federation

6. Irkutsk Antiplague Research Institute of Siberia and Far East awarded with Order of the Red Banner (Director)

Irkutsk, Irkutsk region, Russian Federation

Type:

Article

DOI:

https://doi.org/10.12737/article_59a614fbe83145.69615594

Pages:

from 69 to 73

Status:

Published

Received:

14.08.2017

Accepted:

24.08.2017

Published:

24.08.2017

Subject area:

UDK 61 Медицина. Охрана здоровья

Language:

Russian

Keywords:

pechen', Yersinia restis, gepatocity, mitoz, granulema

Abstract and keywords

Abstract (English):
Izuchena dinamika patomorfologicheskih izmeneniy pecheni eksperimental'nyh zhivotnyh pri infekcionnom processe, vyzvannom Yersinia restis s raznym plazmidnym spektrom. Pokazana variabel'nost' povrezhdeniy pecheni v zavisimosti ot plazmid-associirovannoy virulentnosti vozbuditelya infekcii. Podtverzhdeno, chto shtamm Y. restis, obladayuschiy tremya osnovnymi plazmidami pYP (6 mDa), pYV (45 mDa), pYT (61 mDa), vyzyvaet naibolee ostruyu generalizovannuyu formu zabolevaniya, kotoraya, kak pravilo, zakanchivaetsya letal'nym ishodom.

Keywords:
pechen', Yersinia restis, gepatocity, mitoz, granulema

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References

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2. Manskikh VN. (2016). Pathomorphology of laboratory mouse liver: hidden dangers on the way to a correct diagnosis [Patomorfologiya pecheni laboratornoy myshi: podvodnye kamni na puti k vernomu diagnozu]. Available at: http://ruslasa.ru/wp-content/uploads/Patologiya-pecheni-metodichka-dlya-sayta.pdf.

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8. Yaschuk ND, Vengerov YY. (1999). Lectures on infectious diseases [ Lektsii po infektsionnym boleznyam]. Moskva, (2), 452 p.

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