CHARACTERIZATION OF THE RATE OF GROWTH OF MYCOBACTERIA TUBERCULOSIS ON DENSE NUTRIENT MEDIA IN PATIENTS WITH TUBERCULOSIS
Rubrics: MICROBIOLOGY AND VIROLOGY
Authors:
1.
Irkutsk State Medical Academy of Postgraduate Education
(Department of Tuberculosis, Head)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
2.
Irkutsk State Medical Academy of Postgraduate Education
(Department of Tuberculosis, Associate Professor)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
3.
Irkutsk State Medical Academy of Postgraduate Education
(Department of Epidemiology and Microbiology, Head)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
4.
Irkutsk State Medical Academy of Postgraduate Education
(Department of Tuberculosis, Associate Professor)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
5.
Irkutsk State Medical Academy of Postgraduate Education
(Department of Epidemiology and Microbiology, Professor)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
Type:
Article
Pages:
from 83
to 87
Status:
Published
Received:
19.10.2017
Accepted:
22.11.2017
Published:
22.11.2017
Subject area:
UDK 61 Медицина. Охрана здоровья
Language:
Russian
Keywords:
tuberkulez, zhiznesposobnost' mikobakteriy tuberkuleza, lekarstvennaya ustoychivost', VICh-infekciya
Abstract (English):
Issledovanie zhiznesposobnosti provedeno na osnovanii skorosti i massivnosti rosta kul'tur mikobakteriy tuberkuleza (MBT), poluchennyh iz mokroty bol'nyh tuberkulezom organov dyhaniya na plotnyh pitatel'nyh sredah Levenshteyna-Yensena. Pri skorosti rosta menee 30 dney i kolichestve bolee 100 koloniy na pitatel'noy srede zhiznesposobnost' ocenivalas' kak vysokaya, pri skorosti rosta bolee 30 dney i massivnosti menee 20 koloniy – nizkaya. Iz 5945 kul'tur 2193 polucheno ot vpervye vyyavlennyh, 3752 - ot ranee lechennyh pacientov - zhiteley Irkutskoy oblasti. 2171 kul'tura (36,5%) imeli vysokuyu, 3021 (50,8%) - nizkuyu i 753 (12,7%) – srednyuyu stepeni zhiznesposobnosti. Lekarstvenno-ustoychivye shtammy vozbuditelya, v tom chisle s mnozhestvennoy lekarstvennoy ustoychivost'yu, chasche associiruyutsya s vysokoy stepen'yu zhiznesposobnosti, chem lekarstvenno-chuvstvitel'nye. Vysokaya stepen' zhiznesposobnosti vozbuditelya chasche opredelena pri vpervye vyyavlennom tuberkuleze vnutrigrudnyh limfaticheskih uzlov, fibrozno-kavernoznom i infil'trativnom tuberkuleze. U ranee lechennyh pacientov vysokaya zhiznesposobnost' MBT chasche vyyavlyalas' pri fibrozno-kavernoznom i infil'trativnom tuberkuleze, nizkaya – pri tuberkuleze vnutrigrudnyh limfaticheskih uzlov. Vse pacienty s tuberkulezom vnutrigrudnyh limfaticheskih uzlov imeli soputstvuyuschuyu VICh-infekciyu.
Issledovanie zhiznesposobnosti provedeno na osnovanii skorosti i massivnosti rosta kul'tur mikobakteriy tuberkuleza (MBT), poluchennyh iz mokroty bol'nyh tuberkulezom organov dyhaniya na plotnyh pitatel'nyh sredah Levenshteyna-Yensena. Pri skorosti rosta menee 30 dney i kolichestve bolee 100 koloniy na pitatel'noy srede zhiznesposobnost' ocenivalas' kak vysokaya, pri skorosti rosta bolee 30 dney i massivnosti menee 20 koloniy – nizkaya. Iz 5945 kul'tur 2193 polucheno ot vpervye vyyavlennyh, 3752 - ot ranee lechennyh pacientov - zhiteley Irkutskoy oblasti. 2171 kul'tura (36,5%) imeli vysokuyu, 3021 (50,8%) - nizkuyu i 753 (12,7%) – srednyuyu stepeni zhiznesposobnosti. Lekarstvenno-ustoychivye shtammy vozbuditelya, v tom chisle s mnozhestvennoy lekarstvennoy ustoychivost'yu, chasche associiruyutsya s vysokoy stepen'yu zhiznesposobnosti, chem lekarstvenno-chuvstvitel'nye. Vysokaya stepen' zhiznesposobnosti vozbuditelya chasche opredelena pri vpervye vyyavlennom tuberkuleze vnutrigrudnyh limfaticheskih uzlov, fibrozno-kavernoznom i infil'trativnom tuberkuleze. U ranee lechennyh pacientov vysokaya zhiznesposobnost' MBT chasche vyyavlyalas' pri fibrozno-kavernoznom i infil'trativnom tuberkuleze, nizkaya – pri tuberkuleze vnutrigrudnyh limfaticheskih uzlov. Vse pacienty s tuberkulezom vnutrigrudnyh limfaticheskih uzlov imeli soputstvuyuschuyu VICh-infekciyu.
Keywords:
tuberkulez, zhiznesposobnost' mikobakteriy tuberkuleza, lekarstvennaya ustoychivost', VICh-infekciya
tuberkulez, zhiznesposobnost' mikobakteriy tuberkuleza, lekarstvennaya ustoychivost', VICh-infekciya
1. Spislit zhiznesposobnost' vozbuditelya
