<?xml version="1.0"?>
<!DOCTYPE article
PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20190208//EN"
       "JATS-journalpublishing1.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.4" xml:lang="en">
 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Acta biomedica scientifica</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Acta biomedica scientifica</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Acta biomedica scientifica</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2541-9420</issn>
   <issn publication-format="online">2587-9596</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">14788</article-id>
   <article-id pub-id-type="doi">10.12737/23746</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>Клиническая медицина</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>Clinical Medicine</subject>
    </subj-group>
    <subj-group>
     <subject>Клиническая медицина</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">USE OF TRANSCRANIAL MAGNETIC STIMULATION IN CHILDREN WITH CONSEQUENCES OF PERINATAL BRAIN LESIONS</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>ПРИМЕНЕНИЕ ТРАНСКРАНИАЛЬНОЙ МАГНИТНОЙ СТИМУЛЯЦИИ У ДЕТЕЙ С ПОСЛЕДСТВИЯМИ ПЕРИНАТАЛЬНЫХ ПОРАЖЕНИЙ ЦНС</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Тимофеева</surname>
       <given-names>Ольга Петровна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Timofeeva</surname>
       <given-names>Olga Петровна</given-names>
      </name>
     </name-alternatives>
     <email>orc@irk.ru</email>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Алимова</surname>
       <given-names>Елена Борисовна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Alimova</surname>
       <given-names>Elena Борисовна</given-names>
      </name>
     </name-alternatives>
     <email>alimiv68@mail.ru</email>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Шпрах</surname>
       <given-names>Владимир Викторович</given-names>
      </name>
      <name xml:lang="en">
       <surname>Shprakh</surname>
       <given-names>Vladimir Viktorovich</given-names>
      </name>
     </name-alternatives>
     <email>irkmapo@irk.ru</email>
     <bio xml:lang="ru">
      <p>доктор медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>doctor of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Лаврик</surname>
       <given-names>Сергей Юрьевич</given-names>
      </name>
      <name xml:lang="en">
       <surname>Lavrik</surname>
       <given-names>Sergey Юрьевич</given-names>
      </name>
     </name-alternatives>
     <email>slavrick@gmail.com</email>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Сабирова</surname>
       <given-names>Руфина Росековна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Sabirova</surname>
       <given-names>Rufina Росековна</given-names>
      </name>
     </name-alternatives>
     <email>orcdiagnost@yandex.ru</email>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Иркутской государственной медицинской академии последипломного образования</institution>
     <city>Иркутск</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Irkutsk State Medical Academy of Postgraduate Education</institution>
     <city>Irkutsk</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2016-12-23T00:00:00+03:00">
    <day>23</day>
    <month>12</month>
    <year>2016</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2016-12-23T00:00:00+03:00">
    <day>23</day>
    <month>12</month>
    <year>2016</year>
   </pub-date>
   <volume>1</volume>
   <issue>6</issue>
   <fpage>71</fpage>
   <lpage>75</lpage>
   <self-uri xlink:href="https://zh-szf.ru/en/nauka/article/14788/view">https://zh-szf.ru/en/nauka/article/14788/view</self-uri>
   <abstract xml:lang="ru">
    <p>Обследовано 1249детей 5–10лет с последствиями перинатальных поражений ЦНС, 230 из которых пролечено методом транскраниальной магнитной стимуляции (ТМС). Эффективность терапии в пределах 55–60% в отношении показателей речевой сферы и психологического статуса достигнута при совместном проведении сеансов ТМС с коррекционными занятиями. Эффективность монотерапии ТМС составила 30–35%. Показаны достаточная клиническая эффективность и безопасность методики, возможность проведения сеансов ТМС на фоне курсовой нейропротективной терапии у детей с ДЦП. </p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>1249children of 5–10years (716boys, 533girls) with consequences of perinatal lesions of the CNS were examined, 230 of them were treated with the transcranial magnetic stimulation method (TMS). Selection of the TMS regimens was carried out taking into account the specific clinical neurophysiological features of the patients both as monotherapy, as well as a part of complex neurorehabilitation. For example, when intensifying of the synchronizing influences of tha-lamic structures and EEG signs of a delay of formation of electrical cortical rhythmicity, in children with developmental dysphasia and difficulties of school training, a high-pitched stimulation in the projection of the sensomotor and speech zones of a cerebral cortex was chosen; when intensifying of desynchronization influences of a reticular formation of a brainstem; at motor type of a developmental dysphasia and clinical signs of ADHD syndrome, a low-frequency regimen of stimulation of front-parietal and central areas of a cerebral cortex were chosen. Efficiency of therapy within 55–60% concerning indicators of the speech sphere and the psychological status is reached at sessions of TMS together with correctional occupations with auxiliary specialists of the rehabilitation center – speech pathologists and psychologists. Efficiency of monotherapy of TMS in children with retardation of psycho-speech development made 30–35%. Sufficient clinical performance and safety of the technique, a possibility of holding sessions of TMS against the background of course neuroprotective therapy at children with cerebral palsy is shown.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>последствия перинатальных поражений центральной нервной системы</kwd>
    <kwd>детский цере-бральный паралич</kwd>
    <kwd>минимальная мозговая дисфункция</kwd>
    <kwd>речевые нарушения</kwd>
    <kwd>транскра-ниальная магнитная стимуляция</kwd>
    <kwd>ТМС</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>consequences of perinatal brain lesions</kwd>
    <kwd>cerebral palsy</kwd>
    <kwd>minimal brain dysfunction</kwd>
    <kwd>language impairment</kwd>
    <kwd>transcranial magnetic stimulation</kwd>
    <kwd>TMS</kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <p></p>
 </body>
 <back>
  <ref-list>
   <ref id="B1">
    <label>1.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">БатышеваТ.Т., БыковаО.В., ВиноградовА.В. Детский церебральный паралич - современные представления о проблеме //Русский медицинский журнал. - 2012. - No8. - С.401-405</mixed-citation>
     <mixed-citation xml:lang="en">BatyshevaTT, BykovaOV, VinogradovAV (2012). Cerebral palsy - modern conceptions of a problem [Detskiy tserebral’nyy paralich - sovremennye predstavleniya o probleme]. Russkiy meditsinskiy zhurnal,(8), 401-405.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B2">
    <label>2.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">ВейнА.М. Неврология неспецифических систем мозга. - СПб.: Книга по требованию, 2012. - 122с.</mixed-citation>
     <mixed-citation xml:lang="en">VeynAM (2012). Neurology of nonspecific systems of the brain [Nevrologiya nespetsificheskikh sistem mozga], 122</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B3">
    <label>3.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">ВойтенковВ.Б., СкрипченкоН.В., КлимкинА.В., ИвановаМ.В., ПульманН.Ф., ЧеркашинаИ.В. Нейро-физиологические методики в мониторинге эффек-тивности нейрореабилитации у детей //Курортная медицина. - 2016 - No2. - С.23-26</mixed-citation>
     <mixed-citation xml:lang="en">VoytenkovVB, SkripchenkoNV, KlimkinAV, Ivano-vaMV, PulmanNF, CherkashinaIV (2016). Neurophysi-ological techniques in monitoring of efficiency of neurore-habilitation in children [Neyrofiziologicheskie metodiki v monitoringe effektivnosti neyroreabilitatsii u detey]. Kurortnaya meditsina, (2), 23-26.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B4">
    <label>4.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">ГузеваВ.И. Детская неврология. Вып.1. Кли-нические рекомендации. - М.: ООО «МК», 2014.- 328с.</mixed-citation>
     <mixed-citation xml:lang="en">GuzevaVI (2014). Children’s neurology. Issue 1: clini-cal references [Detskaya nevrologiya. Vyp. 1. Klinicheskie rekomendatsii], 328.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B5">
    <label>5.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">ЗаваденкоН.Н., КозловаЕ.В., КолтуновИ.Е. Дис-фазия развития: оценка эффективности лекарствен-ной терапии //Журн. неврологии и психиатрии им. С.С.Корсакова. - 2012. - No7. - С.90-95.</mixed-citation>
     <mixed-citation xml:lang="en">ZavadenkoNN, KozlovaEV, KoltunovIE (2012). Developmental dysphasia: medicinal therapy efficiency assessment [Disfaziya razvitiya: otsenka effektivnosti lekarstvennoy terapii]. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, (7), 90-95</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B6">
    <label>6.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">ИскраД.А., ФрунзаД.Н., БодроваТ.В. Транскра-ниальная магнитная стимуляция моторной коры при головных болях напряжения //Вестник Российской военно-медицинской академии. - 2012. - No2(38). - С.79-83.</mixed-citation>
     <mixed-citation xml:lang="en">IskraDA, FrunzaDN, BodrovaTV (2012). Transcranial magnetic stimulation of the motor cortex in chronic tension-type headaches [Transkranial’naya magnitnaya stimulyatsiya motornoy kory pri golovnykh bolyakh napryazheniya]. Vestnik Rossiyskoy voenno-meditsinskoy akademii, 2(38), 79-83.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B7">
    <label>7.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">НемковаС.А. Детский церебральный паралич: Современные технологии в комплексной диагности-ке и реабилитации когнитивных расстройств. - М.: Медпрактика-М, 2013. - 442с.</mixed-citation>
     <mixed-citation xml:lang="en">NemkovaSA (2013). Cerebral palsy: Modern technologies in complex diagnostics and rehabilitation of cognitive disorders [Detskiy tserebral’nyy paralich: Sovremennye tekhnologii v kompleksnoy diagnostike i reabilitatsii kognitivnykh rasstroystv], 442.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B8">
    <label>8.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">НикитинС.С., КуренковА.Л. Методические ос-новы транскраниальной магнитной стимуляции. - М.: САШКО, 2003 - 378с</mixed-citation>
     <mixed-citation xml:lang="en">NikitinSS, KurenkovAL (2003) Methodical basics of transcranial magnetic stimulation[Metodicheskie osnovy transkranial’noy magnitnoy stimulyatsii], 378.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B9">
    <label>9.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">НьокиктьенЧ. Детская поведенческая невро-логия. В 2-х томах. - М.: Теревинф, 2009. - Т.1. - 288с</mixed-citation>
     <mixed-citation xml:lang="en">.NjiokiktjienC (2009). Pediatric behavioral neurology [Detskaya povedencheskaya nevrologiya. V 2-kh tomakh], (1), 288</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B10">
    <label>10.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">РозаМ.А., РозаМ.О. Лечебная ритмическая транскраниальная магнитная стимуляция: Практи-ческое руководство. - Иваново: Нейрософт, 2012.- 48с.</mixed-citation>
     <mixed-citation xml:lang="en">RozaMA, RozaMO (2012). Medical rhythmic transcranial magnetic stimulation: Practical guidance [Lechebnaya ritmicheskaya transkranial’naya magnitnaya stimulyatsiya: Prakticheskoe rukovodstvo], 48</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B11">
    <label>11.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru"></mixed-citation>
     <mixed-citation xml:lang="en">RossiniPM, RossiS (2007). Transcranial magnetic stimulation: diagnostic, therapeutic, and research potential. Neurology, 68(7), 484-488.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B12">
    <label>12.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru"></mixed-citation>
     <mixed-citation xml:lang="en">ТanXST (2005). Developmental dysphasia, 357</mixed-citation>
    </citation-alternatives>
   </ref>
  </ref-list>
 </back>
</article>
