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 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Medical Radiology and radiation safety</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Medical Radiology and radiation safety</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Медицинская радиология и радиационная безопасность</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">1024-6177</issn>
   <issn publication-format="online">2618-9615</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">44246</article-id>
   <article-id pub-id-type="doi">10.12737/1024-6177-2021-66-1-63-68</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>Ядерная медицина</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>Nuclear medicine</subject>
    </subj-group>
    <subj-group>
     <subject>Ядерная медицина</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">Prospects for Using Radionuclide Research Methods for Diagnosing and Evaluating Effectiveness  of Treating Consequences of Coronavirus Diseasr (COVID-19</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>ПЕРСПЕКТИВЫ ИСПОЛЬЗОВАНИЯ РАДИОНУКЛИДНЫХ МЕТОДОВ  ИССЛЕДОВАНИЯ ДЛЯ ДИАГНОСТИКИ И ОЦЕНКИ ЭФФЕКТИВНОСТИ  ЛЕЧЕНИЯ ПОСЛЕДСТВИЙ ПЕРЕНЕСЕННОЙ НОВОЙ  КОРОНАВИРУСНОЙ ИНФЕКЦИИ</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Кудрявцев</surname>
       <given-names>А Д</given-names>
      </name>
      <name xml:lang="en">
       <surname>Kudryavtsev</surname>
       <given-names>A D</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Кондаков</surname>
       <given-names>А К</given-names>
      </name>
      <name xml:lang="en">
       <surname>Kondakov</surname>
       <given-names>A K</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Корвяков</surname>
       <given-names>C А</given-names>
      </name>
      <name xml:lang="en">
       <surname>Korvyakov</surname>
       <given-names>S A</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-3"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Созыкин</surname>
       <given-names>А. В.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Sozykin</surname>
       <given-names>A. V.</given-names>
      </name>
     </name-alternatives>
     <bio xml:lang="ru">
      <p>доктор медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>doctor of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-4"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Никитин</surname>
       <given-names>П. А.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Nikitin</surname>
       <given-names>P. A.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-5"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Юдин</surname>
       <given-names>А Л</given-names>
      </name>
      <name xml:lang="en">
       <surname>Yudin</surname>
       <given-names>A L</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-6"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Знаменский</surname>
       <given-names>И. А.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Znamenskiy</surname>
       <given-names>I. A.</given-names>
      </name>
     </name-alternatives>
     <bio xml:lang="ru">
      <p>доктор медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>doctor of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-7"/>
     <xref ref-type="aff" rid="aff-8"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Центральная клиническая больница Российской академии наук, Россия, Москва</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Central Clinical Hospital of Russian Academy of Sciences, Moscow, Russia</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">Центральная клиническая больница Российской академии наук, Россия, Москва</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Central Clinical Hospital of Russian Academy of Sciences, Moscow, Russia</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-3">
    <aff>
     <institution xml:lang="ru">Центральная клиническая больница Российской академии наук, Россия, Москва</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Central Clinical Hospital of Russian Academy of Sciences, Moscow, Russia</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-4">
    <aff>
     <institution xml:lang="ru">Центральная клиническая больница РАН</institution>
     <city>Москва</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Central Clinical Hospital</institution>
     <city>Moscow</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-5">
    <aff>
     <institution xml:lang="ru">Центральная клиническая больница РАН</institution>
     <city>Москва</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Central Clinical Hospital</institution>
     <city>Moscow</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-6">
    <aff>
     <institution xml:lang="ru">Российский национальный исследовательский медицинский университет им Н.И. Пирогова  Минздрава, Россия, Москва</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">N.I.Pirogov Russian National Research Medical University of the Ministry of Health of Russia, Moscow, Russia</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-7">
    <aff>
     <institution xml:lang="ru">Центральная клиническая больница РАН</institution>
     <city>Москва</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Central Clinical Hospital</institution>
     <city>Moscow</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-8">
    <aff>
     <institution xml:lang="ru">Российский национальный исследовательский медицинский университет имени Н.И. Пирогова</institution>
     <city>Москва</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Pirogov Russian National Research Medical University</institution>
     <city>Moscow</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <volume>66</volume>
   <issue>1</issue>
   <fpage>63</fpage>
   <lpage>68</lpage>
   <self-uri xlink:href="https://zh-szf.ru/en/nauka/article/44246/view">https://zh-szf.ru/en/nauka/article/44246/view</self-uri>
   <abstract xml:lang="ru">
    <p>Цель: Определить роль методов ядерной медицины в диагностике и контроле качества лечения и реабилитации пациентов с осложнениями после перенесенной новой коронавирусной инфекции &#13;
Дан краткий анализ заболеваемости COVID-19, диагностики, лечения и реабилитации пациентов, страдающих от последствий перенесенной новой коронавирусной инфекции после окончания пандемии. Освещены основные осложнения и последствия новой коронавирусной инфекции. Наиболее распространенным клиническим проявлением коронавирусной инфекции является двусторонняя интерстициальная пневмония, одним из осложнений которой является развитие острого респираторного дистресс синдрома, освещен его патогенез. Также отмечено, что ведущим звеном в развитии заболевания является системное поражение эндотелиальной стенки сосудов, что является причиной тромбоза и его осложнений, в первую очередь тромбоэмболии лёгочной артерии, ишемическим инфарктам головного мозга и сердечно-сосудистым катастрофам. Отмечена также роль гипериммунного ответа на вирусемию.&#13;
Описаны конкретные методы радионуклидной диагностики применительно к отдельным органам и системам: респираторной, сердечно-сосудистой, головному мозгу и другим. Определена необходимость диагностики и контроля качества лечения и реабилитации пациентов с поствоспалительными изменениями паренхимы внутренних органов и снижением их функциональной способности за счет склеротических изменений, пациентов с изменениями состояния в связи с переходом воспаления в хроническую стадию, а также с гиперактивным иммунным ответом на воспалительные изменения.&#13;
Заключение: На этапе диагностики и лечения последствий перенесенной коронавирусной инфекции и последующей реабилитации методы молекулярной визуализации имеют существенное значение в комплексе исследований.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>Purpose:  to determine the role of nuclear medicine methods in the diagnosis and quality control of treatment and rehabilitation of patients with complications after coronavirus diseasr (COVID-19)&#13;
The article provides a brief analysis of the incidence of COVID-19 and highlights the role of diagnosis, treatment and rehabilitation of patients suffering from the consequences of coronavirus diseasr after the end of the pandemic. The most common clinical manifestation of coronavirus diseasr is bilateral interstitial pneumonia, one of the complications of which is the development of acute respiratory distress syndrome, its pathogenesis is highlighted. It is also noted that the leading link in the development of the disease is a systemic lesion of the endothelial vascular wall, which is the cause of thrombosis and its complications, primarily pulmonary embolism, ischemic brain infarctions and cardiovascular catastrophes. &#13;
Specific methods of radionuclide diagnostics are described for individual organs and systems: respiratory, cardiovascular, brain, and others. The need to diagnose and control the quality of treatment and rehabilitation of patients with post-inflammatory changes in the parenchyma of internal organs and a decrease in their functional ability due to sclerotic changes, patients with changes in the state due to the transition of inflammation to the chronic stage, as well as with an overactive immune response to inflammatory changes.&#13;
Conclusion: at the stage of diagnosis and treatment of the consequences of a previous coronavirus diseasr and subsequent rehabilitation, molecular imaging methods are essential in a complex of studies.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>COVID-19</kwd>
    <kwd>радионуклидная диагностика</kwd>
    <kwd>респираторная система</kwd>
    <kwd>сердечно-сосудистая система</kwd>
    <kwd>головной мозг</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>COVID-19</kwd>
    <kwd>diagnostics nuclear medicine</kwd>
    <kwd>respiratory system</kwd>
    <kwd>cardiovascular system</kwd>
    <kwd>brain</kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <p></p>
 </body>
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