THE LIPIDS OF BIOLOGICAL MEMBRANES (LITERATURE REVIEW)
Rubrics: BIOLOGICAL CHEMISTRY
Authors:
1.
Irkutsk Scientific Center of Surgery and Traumatology
(laboratory of Pathophysiology of Functional Systems, Junior Research Officer)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
2.
Irkutsk Scientific Center of Surgery and Traumatology
(Laboratory of Pathophysiology of Functional Systems, head)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
3.
Irkutsk Scientific Center of Surgery and Traumatology
(Laboratory of Pathophysiology of Functional Systems, Junior Research Officer)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
4.
Irkutsk Scientific Center of Surgery and Traumatology
(Laboratory of Pathophysiology of Functional Systems, Senior Research Officer)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
5.
Irkutsk, Irkutsk region, Russian Federation
Type:
Article
Pages:
from 43
to 49
Status:
Published
Received:
19.10.2017
Accepted:
22.11.2017
Published:
22.11.2017
Subject area:
UDK 61 Медицина. Охрана здоровья
Language:
Russian
Keywords:
eritrocit, membrana, fosfolipidy, lipidnyy bisloy
Abstract (English):
V dannom obzore predstavleny obschie principy stroeniya i funkciy lipidnogo komponenta citoplazmaticheskih membran. Perechisleny suschestvuyuschie teorii, kotorye prinyato nazyvat' modelyami biologicheskih membran. Rassmotreny svoystva prisuschie lipidam i belkam i chto na nih vliyaet. Opisyvaetsya s himicheskoy tochki zreniya sostav i struktura harakteristicheskih grupp fosfolipidov, asimmetrichnoe raspolozhenie lipidov v membrane eritrocitov ego podderzhanie i fiziologicheskaya znachimost'. V dopolnenie opisyvaetsya, chto vokrug atomov ugleroda v uglevodorodnyh cepyah zhirnyh kislot kak na osi, razlichnye uchastki imeyut vozmozhnost' vraschat'sya, to est' cepi imeyut vse shansy prebyvat' v samyh raznyh konfiguraciyah. Tak zhe rassmotreny naibolee znachimye belki obespechivayuschie ionnyy gomeostaz eritrocita. Plazmaticheskaya membrana obladaet unikal'noy receptorno-signal'noy funkciey, reguliruyuschey osnovnye kletochnye processy, povrezhdenie kotoroy mozhet privesti k gibeli kletok. Privedeny dannye o znachenii lipidnogo sloya membran eritrocitov v izuchenii molekulyarnyh mehanizmov razvitiya patologicheskih sostoyaniy. Vliyanie na kletki tkaney i organov razlichnyh povrezhdayuschih faktorov vyzyvaet zapusk universal'nogo otveta. Predstavleny osnovnye tipovye processy, privodyaschie k strukturno-funkcional'nym izmeneniyam plazmaticheskih membran kletok.
V dannom obzore predstavleny obschie principy stroeniya i funkciy lipidnogo komponenta citoplazmaticheskih membran. Perechisleny suschestvuyuschie teorii, kotorye prinyato nazyvat' modelyami biologicheskih membran. Rassmotreny svoystva prisuschie lipidam i belkam i chto na nih vliyaet. Opisyvaetsya s himicheskoy tochki zreniya sostav i struktura harakteristicheskih grupp fosfolipidov, asimmetrichnoe raspolozhenie lipidov v membrane eritrocitov ego podderzhanie i fiziologicheskaya znachimost'. V dopolnenie opisyvaetsya, chto vokrug atomov ugleroda v uglevodorodnyh cepyah zhirnyh kislot kak na osi, razlichnye uchastki imeyut vozmozhnost' vraschat'sya, to est' cepi imeyut vse shansy prebyvat' v samyh raznyh konfiguraciyah. Tak zhe rassmotreny naibolee znachimye belki obespechivayuschie ionnyy gomeostaz eritrocita. Plazmaticheskaya membrana obladaet unikal'noy receptorno-signal'noy funkciey, reguliruyuschey osnovnye kletochnye processy, povrezhdenie kotoroy mozhet privesti k gibeli kletok. Privedeny dannye o znachenii lipidnogo sloya membran eritrocitov v izuchenii molekulyarnyh mehanizmov razvitiya patologicheskih sostoyaniy. Vliyanie na kletki tkaney i organov razlichnyh povrezhdayuschih faktorov vyzyvaet zapusk universal'nogo otveta. Predstavleny osnovnye tipovye processy, privodyaschie k strukturno-funkcional'nym izmeneniyam plazmaticheskih membran kletok.
Keywords:
eritrocit, membrana, fosfolipidy, lipidnyy bisloy
eritrocit, membrana, fosfolipidy, lipidnyy bisloy
1. Spislit_lipidy
