COMPARISON OF MICROECOLOGICAL INTESTINAL INDICES IN CHILDREN WITH DIFFERENT VALUE OF BODY MASS INDEX
Rubrics: PEDIATRICS
Authors:
1.
Scientific Centre for Family Health and Human Reproduction Problems
(Laboratory of Microecology and Microbiome, Research Officer)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
2.
Scientific Centre for Family Health and Human Reproduction Problems
(Gastroenterology Unit of the Clinic, Head)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
3.
Scientific Centre for Family Health and Human Reproduction Problems
(Laboratory of Microecology and Microbiome, Junior Research Officer)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
4.
Scientific Centre for Family Health and Human Reproduction Problems
(Laboratory of Microecology and Microbiome, Head)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
5.
Scientific Centre for Family Health and Human Reproduction Problems
(Laboratory of Pediatrics and Cardiovascular Pathology, Head)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
6.
Scientific Centre for Family Health and Human Reproduction Problems
(direktor)
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
Type:
Article
Pages:
from 111
to 115
Status:
Published
Received:
19.10.2017
Accepted:
22.11.2017
Published:
22.11.2017
Subject area:
UDK 61 Медицина. Охрана здоровья
Language:
Russian
Keywords:
Indeks massy tela, izbytochnaya i nizkaya massa tela, disbioz kishechnika, deti
Abstract (English):
Indeks massy tela (IMT) yavlyaetsya odnim iz klyuchevyh i v tozhe vremya prostyh i znachimyh pokazateley sostoyaniya organizma cheloveka. Kak bol'shie, tak i malye velichiny IMT associirovany s vysokim urovnem zabolevaemosti. Cel' issledovaniya: ispol'zuya velichinu IMT kak kriteriy sravneniya proanalizirovat' mikroekologicheskie narusheniya kishechnogo biocenoza u detey raznogo vozrasta. Metody issledovaniya. Issledovan koprologicheskiy material ot 158 detey i podrostkov v vozraste ot 5 do 17 let (iz nih 77 mal'chikov i 81 devochka). Material byl raspredelen na tri gruppy sravneniya v zavisimosti ot velichiny IMT: pervaya gruppa s deficitom massy tela (DMT) (n=34), 2 gruppa s izbytochnym vesom i ozhireniem (IzbMT) (n=37), tret'ya gruppa s normal'nym vesom (NMT) (n=87). Rezul'taty. Pokazano, chto u bolee 80% detey s razlichnoy velichinoy IMT registrirovalis' disbioticheskie narusheniya kishechnoy mikrobioty 1 i 2 stepeni. Odnako v gruppe detey s NMT chastota vyyavleniya kishechnogo disbioza byla znachitel'no men'shey, a v gruppe detey s deficitom vesa disbioticheskie narusheniya vstrechalis' znachitel'no chasche, chem u detey s izbytkom vesa i ozhireniem (r<0,05). U detey s DMT nablyudalos' ne tol'ko povyshenie koncentracii UPB, no i uvelichenie chastoty vstrechaemosti otdel'nyh predstaviteley semeystva Enterobacteriaceae, v 58,8 % sluchaev registrirovalis' dvuh i trehkomponentnye associacii uslovno-patogennyh bakteriy (UPB), chto yavlyaetsya pokazatelem vyrazhennyh narusheniy formirovaniya mikrobiocenoza kishechnika. Poluchennye dannye pokazyvayut, chto pri ocenke sostoyaniya kishechnoy mikroflory v komplekse s drugimi issledovaniyami mozhno ispol'zovat' IMT kak vazhnyy kriteriy, otrazhayuschiy tyazhest' techeniya zabolevaniya.
Indeks massy tela (IMT) yavlyaetsya odnim iz klyuchevyh i v tozhe vremya prostyh i znachimyh pokazateley sostoyaniya organizma cheloveka. Kak bol'shie, tak i malye velichiny IMT associirovany s vysokim urovnem zabolevaemosti. Cel' issledovaniya: ispol'zuya velichinu IMT kak kriteriy sravneniya proanalizirovat' mikroekologicheskie narusheniya kishechnogo biocenoza u detey raznogo vozrasta. Metody issledovaniya. Issledovan koprologicheskiy material ot 158 detey i podrostkov v vozraste ot 5 do 17 let (iz nih 77 mal'chikov i 81 devochka). Material byl raspredelen na tri gruppy sravneniya v zavisimosti ot velichiny IMT: pervaya gruppa s deficitom massy tela (DMT) (n=34), 2 gruppa s izbytochnym vesom i ozhireniem (IzbMT) (n=37), tret'ya gruppa s normal'nym vesom (NMT) (n=87). Rezul'taty. Pokazano, chto u bolee 80% detey s razlichnoy velichinoy IMT registrirovalis' disbioticheskie narusheniya kishechnoy mikrobioty 1 i 2 stepeni. Odnako v gruppe detey s NMT chastota vyyavleniya kishechnogo disbioza byla znachitel'no men'shey, a v gruppe detey s deficitom vesa disbioticheskie narusheniya vstrechalis' znachitel'no chasche, chem u detey s izbytkom vesa i ozhireniem (r<0,05). U detey s DMT nablyudalos' ne tol'ko povyshenie koncentracii UPB, no i uvelichenie chastoty vstrechaemosti otdel'nyh predstaviteley semeystva Enterobacteriaceae, v 58,8 % sluchaev registrirovalis' dvuh i trehkomponentnye associacii uslovno-patogennyh bakteriy (UPB), chto yavlyaetsya pokazatelem vyrazhennyh narusheniy formirovaniya mikrobiocenoza kishechnika. Poluchennye dannye pokazyvayut, chto pri ocenke sostoyaniya kishechnoy mikroflory v komplekse s drugimi issledovaniyami mozhno ispol'zovat' IMT kak vazhnyy kriteriy, otrazhayuschiy tyazhest' techeniya zabolevaniya.
Keywords:
Indeks massy tela, izbytochnaya i nizkaya massa tela, disbioz kishechnika, deti
Indeks massy tela, izbytochnaya i nizkaya massa tela, disbioz kishechnika, deti
1. Spislit sravnenie mikroekolog pokazat
