employee
Chelyabinsk State University, Chelyabinsk, Russia
Russian Federation
VAC 14.02.2003 Общественное здоровье и здравоохранение
VAC 14.02.2004 Медицина труда
UDK 61 Медицина. Охрана здоровья
GRNTI 76.01 Общие вопросы медицины и здравоохранения
GRNTI 76.29 Клиническая медицина
GRNTI 76.35 Прочие отрасли медицины и здравоохранения
GRNTI 87.25 Воздействие антропогенных измен. окруж. среды на здоровье и социально-трудовой потенциал населения
OKSO 31.06.2001 Клиническая медицина
OKSO 31.08.71 Организация здравоохранения и общественное здоровье
OKSO 32.04.01 Общественное здравоохранение
BBK 51 Социальная гигиена и организация здравоохранения. Гигиена. Эпидемиология
BBK 54 Клиническая медицина
BBK 56 Клиническая медицина
BBK 57 Клиническая медицина
BBK 58 Прикладные отрасли медицины
TBK 5706 Социальная гигиена и организация здравоохранения
TBK 5708 Гигиена и санитария. Эпидемиология. Медицинская экология
TBK 5734 Медицинская радиология и рентгенология
TBK 577 Другие отрасли медицины
BISAC MED080000 Radiology, Radiotherapy & Nuclear Medicine
Purpose: Assessment of solid cancer incidence risk in the cohort of exposed population on the territory of the East Urals radioactive trace over the period of follow-up from 1957 to 2014 with the use of the individual doses provided by the latest TRDS dosimetry system. Material and methods: The explosion of the liquid radioactive waste storage tank at the «Mayak» Production Association on 29 September 1957 led to the pollution of the territories of the Chelyabinsk and Sverdlovsk Regions and the formation of the EURT, and the population residing on its territory was subjected to protracted chronic external and internal exposure. The analyzed cohort includes 21,384 people, 2,055 of whom received additional radiation before the 1957 accident due to residing in one of the Techa River settlements. The mean dose to the stomach for the members of the EURT cohort was 36 mGy, the maximum — 1.13 Gy. The analysis was performed using the DATAB and AMFIT programs (statistical software package EPICURE). A simple parametric model of excess relative risk (ERR) was used. Statistical significance and confidence intervals were obtained using the maximum likelihood method. Results: As a result of the analysis of the solid cancer incidence risk in the EURT cohort during the 57-year follow-up period using the linear model and the 5-year latent period, a statistically significant ERR was obtained which equals to 0.052 / 100 mGy (95 % CI 0.01–0.10, p = 0.02) in the entire EURT cohort. When the group of people additionally exposed on the Techa River before the 1957 accident was excluded from the cohort, the risk became insignificant. No significant modification of the dose dependence by non-radiation factors was revealed. The obtained results are compared well with the previous studies of the exposed population in the Southern Urals which were conducted in the Urals Research Center for Radiation Medicine, as well as in the world, devoted to the study of the effects of radiation exposure on population.
population, radiation risk, East Urals radioactive trace (EURT), solid cancer, incidence risk, excessive relative risk
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