Chronic migraine is polyetiological and multi-factor disease. There is no consensus about the transformation from episodic to chronic form triggers. Genetic factors, dysfunction of anti-nociceptive systems, gender, the harmful factors are discussed in this work. A high percentage prevalence among the working-age population, expressed degree of decrease in quality of life are forcing scientists to develop new drug and non-drug approaches to the treatment of this disease. Reflexology has a special place in non-drug therapies, including acupuncture, electro-acupuncture, trans-cutaneous electrical nerve stimulation and Su-Jok therapy. Sufficient experience has been accumulated in use of acupuncture in the treatment of chronic pain syndrome in general and chronic forms of primary headaches in particular. Most methods have confirmed the effectiveness that is comparable to drug therapy. The tolerability of these methods, due to their larger physiology, is superior to pharmacotherapy, and the frequency of adverse reactions is minimized. These features contribute to the growth of the worldwide interest in non-drug methods of treatment and new purposes of the researchers must be focused on comparing the effectiveness of methods among themselves, standardization of techniques of reflexology and develop more differentiated approaches to non-drug therapy.
chronic migraine, acupuncture, electro-acupuncture, Su-Jok therapy
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