STEROID OSTEOPOROSIS WITHIN THE FRAMEWORK OF THE ITSENKO-CUSHING DRUG SYNDROME: DEMONSTRATION OF A CLINICAL CASE
Abstract and keywords
Abstract (English):
A case of severe systemic osteoporosis complicated by multiple fractures of the ribs and vertebrae in a young patient with late diagnosis of Still's disease as a result of independent long-term uncontrolled use of corticosteroids is presented. Lack of medical supervision, taking a high dose (35 mg / day) of prednisolone without recommendation and control of treatment led to untimely recognition and treatment of the underlying disease and the development of irreversible disabling transformations of the skeleton.

Keywords:
osteoporosis, young age, compression fractures of the vertebrae, glucocorticosteroid therapy, late diagnosis, Still's disease
References

1. Rozhinskaya L.Ya. Sistemnyy osteoporoz, M., 2000, 196 s.

2. Toropcova N. V. Glyukokortikoidnyy osteoporoz: diagnostika, profilaktika i lechenie. Nauchno-prakticheskaya revmatologiya. 2014;52(4):423-429.

3. Osteoporoz / pod red. O.M. Lesnyak, L.I. Benevolenskoy. - 2-e izd., pererab. I dop. - M.: GEOTAR-Media, 2009. - 272 s. - (Seriya «Klinicheskie rekomendacii»).

4. Belyaeva, E. A. Rentgenologicheskaya diagnostika i profilaktika perelomov u pacientov so steroidnym osteoporozom. Vestnik novyh medicinskih tehnologiy, 2010, XVII (1), s. 43-44.

5. Vozmozhnosti kostnoy rentgenovskoy densitometrii v klinicheskoy praktike Metodicheskie rekomendacii. Skripnikova I.A., Scheplyagina L.A., i dr., Moskva 2010.

6. Smirnov A. V., Rumyancev A. Sh. Stroenie i funkcii kostnoy tkani v norme i pri patologii. Soobschenie I. // Nefrologiya. - 2014. - T.18, №6. - S.9-25. eLIBRARY ID: 22703984

7. Toropcova NV, Nikitinskaya OA, Smirnov AV. Opyt trehletnego primeneniya genno-inzhenernogo biologicheskogo preparata denosumab dlya lecheniya zhenschin s postmenopauzal'nym osteoporozom: effektivnost', bezopasnost' i priverzhennost' lecheniyu. Nauchno-prakticheskaya revmatologiya. 2017;55(3):261-6. [Toroptsova NV, Nikitinskaya OA, Smirnov AV. Three years' experience with the biological agent denosumab used to treat women with

8. Belaya ZhE, Bilezikian JP, Ershova OB i dr. Vozmozhnosti dlitel'noy terapii postmenopauzal'nogo osteoporoza: obzor rezul'tatov poslednih klinicheskih issledovaniy denosumaba i rezolyuciya soveta ekspertov Rossiyskoy associacii po osteoporozu (RAOP). Osteoporoz i osteopatii. 2018;21(1):17-22. [Belaya ZhE, Bilezikian JP, Ershova OB, et al. Long-term treatment options for postmenopausal osteoporosis: results of recent clinical studies of Denosumab. Osteoporoz i osteopatii. 2018; 21(1):17-22. (In Russ.)].

9. Mazurov V. I., Lesnyak O. M., Belova K. Yu., Ershova O. B., Zotkin E. G., Marchenkova L. A., Kochish A. Yu., Rozhinskaya L. Ya., Skripnikova I. A. Algoritmy vybora terapii osteoporoza pri okazanii pervichnoy mediko-sanitarnoy pomoschi i organizacii l'gotnogo lekarstvennogo obespecheniya otdel'nyh kategoriy grazhdan, imeyuschih pravo na poluchenie gosudarstvennoy social'noy pomoschi. Sistemnyy obzor i rezolyuciya . Profilakticheskaya medicina. 2019;22(1):57-65.

10. Maylyan E.A., Reznichenko N.A., Maylyan D.E. Regulyaciya vitaminom D metabolizma kostnoy tkani. // Medicinskiy vestnik Yuga Rossii. - 2017. - №1. - S.12-20. https://doi.org/10.21886/2219-8075-2017-1-12-20.

11. Ismailov S.I., Hodzhamberdieva D.Sh., Rihsieva N.T. Osteoporoz i nizkoenergeticheskie perelomy sheyki bedra kak oslozhnenie razlichnyh endokrinnyh zabolevaniy. // Mezhdunarodnyy endokrinologicheskiy zhurnal. - 2013. - T.5, №53. - S. 113-120. https://doi.org/10.22141/2224-0721.5.53.2013.84514.

Login or Create
* Forgot password?