Currently, the radiation techniques are dominant in the diagnosis of osteoporosis, among them the dual-energy X-ray absorptiometry (DXA) is the leading. This method is based on the determination of bone mineral density. The article describes a computerized system Standart LS (Russia), which standardizes the parameters of bone mineral density, depending on the type of densitometry equipment and evaluates the results of X-ray densitometry taking into account a regional perspective. The developed program and population database of parameters of bone mineral density were the results of retrospective analysis of the dual-energy X-ray absorptiometry in 1504 women living in Kemerovo region. The dual-energy X-ray absorptiometry was performed with a bone densitometer Lunar-DPX-NT (GE Healthcare, UK). Initially, the bone mineral density of the first-fourth lumbar vertebrae was studied; then, the standardization of other parameters of densitometric systems was carried out (Hologic, Norland). The algorithm of the computer program consists of three phases: the introduction of parameters of bone mineral density, the standardization and the processing according to a type of densitometer and an age of a subject. After data processing, the values of Z-criteria are given out according to the recommendations of the International Society for Clinical Densitometry. The developed computerized system will contribute to a more accurate assessment of bone mineral density in the women, taking into account regional differences.
bone mineral density, dual-energy X-ray absorptiometry (DXA), computerized system of standardization and analysis.
1. Belyaeva E.A., Khadartsev A.A. Vosstanovitel´naya terapiya oslozhnennogo postmenopauzal´nogo osteoporoza: Monografiya. - Tula: Iz-vo «Grif i K», 2010. 248 s.
2. Zakharov I.S., Kolpinskiy G.I., Ivanov V.I. Standartizatsiya pokazateley mineral´noy plotnosti kosti poyasnichnykh pozvonkov (Standart LS). No-mer svidetel´stva o gosudarstvennoy registratsii programmy dlya EVM: 2014662120. Data registratsiya 24.11.2014.
3. Zakharov I. S., Kolpinskiy G. I., Ushakova G. A. Referentnye pokazateli dvukhmernoy mineral´noy plotnosti kosti poyasnichnykh pozvonkov dlya zhitel´nits Kuzbassa. Politravma. 2014. № 3. S. 6368.
4. Lesnyak O.M. Audit sostoyaniya problemy osteoporoza v Rossiyskoy Federatsii. Profilakticheskaya meditsina. 2011. №2. S. 7-10.
5. Osteoporoz: diagnostika, profilaktika i lechenie. / Pod red. O.M. Lesnyak, L.I. Benevolenskoy. 2-e izd., pererab. i dop. M.: GEOTAR-Media, 2009. 272 s.
6. Official Positions of the International Society for Clinical Densitometry and Executive Summary of the 2007 ISCD Position Development Conference / Baim S., Binkley N., Bilezikian J. P., [et al.]. Journal of Clinical Densitometry: Assessment of Skeletal Health. 2008. Vol. 11. №1. P. 75-91.
7. Hernlund E., Svedbom A., Ivergard M., Compston J., Cooper C., Stenmark J., McCloskey E. V., Jonsson B., Kanis J. A. Osteoporosis in the European Union: Medical Management, Epidemiology and Economic Burden. A report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Available at: http://link.springer.com /article/10.1007/s11657-013-0136-1/fulltext.html (accessed 11 March 2013).
8. Universal standardization of bone density measurements: a method with optimal properties for calibration among several instruments / Hui S.L., Gao S., Zhou X.H. [et. al.]. J Bone Miner Res. 1997. 12. R. 1463-1470.
9. Lumbar spine and proximal femur bone mineral density, bone mineral content, and bone area: United States, 2005-2008. Data from the National Health and Nutrition Examination Survey (NHANES). Washington, DC, DHHS Publication No (PHS) 2012-1601. Series 11. No 251. 141 p.
10. These are the Official Positions of the ISCD as updated in 2013. Available at: http://www.iscd.org/ official-positions/2013-iscd-official-positions-adult (accessed April 24, 2014).
11. Reference values of bone mineral density and prevalence of osteoporosis in Chinese adults / Zhang Z-Q., Ho S.C., Chen Z-Q. [et. al.]. Osteoporos Int. 2014. Vol. 25. N2. P. 497-507.
