One of the earliest precursors of the progression of chronic heart failure is the appearance of new neuro-endocrine relations. This contributes to the formation of pathogenic "vicious circle" and clinical manifestation of this disease. The difficulty of diagnosis of chronic heart failure due to the fact that the clinical picture is delayed with respect to changes in the neuro-endocrine system and hemodynamics. There are a number of studies on the neuro-endocrine relations with myocardial infarction, hypertension, diabetes, but there are not the studies on the neuro-endocrine relationships in women with chronic heart failure in modern literature. In this regard, the high relevance of the issue is to identify the features of the neuro-endocrine relations in women with chronic heart failure. It can improve the quality of diagnosis and treatment of this disease. To assess the state of the cardiovascular system the authors used data from a clinical trial objective, ECG, echocardiogram, a study of hormonal status and heart rate variability. This article presents the results of a study of the neuro-endocrine relationships in women with chronic heart failure, with or without coronary heart disease. The results of this research revealed the emergence of new neuro-endocrine relations in women with chronic heart failure and the neuro-endocrine features ratios in patients with coronary heart disease.
chronic heart failure, heart rate variability, neuro-endocrine relationships, coronary heart disease.
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