HYPOXIC ERYTHROCYTOSIS

Yuriy Landyshev; Valeriy Voytsekhovskiy; Nikolay Goborov

doi:10.12737/21462

HYPOXIC ERYTHROCYTOSIS

Published in Bulletin physiology and pathology of respiration · Volume 1, Issue 61 · Pages 107–119 · Rubric: SELECTED REPORTS

DOI: https://doi.org/10.12737/21462

Received: 14.09.2016 Accepted: 15.09.2016 Published: 15.09.2016 Language of publication: RUS

Authors

Yuriy Landyshev

Valeriy Voytsekhovskiy

Nikolay Goborov

Yuriy Landyshev

Valeriy Voytsekhovskiy

Academic degree: doctor of medical sciences

Amur State Medical Academy zaveduyuschiy kafedroy · kafedra gospital'noy terapii s kursom farmakologii · Blagoveshchensk

Nikolay Goborov

Academic degree: candidate of medical sciences

Amur State Medical Academy assistent · kafedra gospital'noy terapii s kursom farmakologii · Blagoveshchensk

ABSTRACT

The article presents a brief review of literature which shows the characteristic of bronchopulmonary and cardiovascular diseases that most often cause secondary absolute hypoxic erythrocytosis. The information about pathogenesis of blood changes at this nosology is given. The principles of differential diagnosis between secondary absolute hypoxic erythrocytosis and chronic myeloproliferative diseases, i.e. polycythemia vera and idiopathic myelofibrosis in erythremia stage are set. As an example three clinical cases of personal experience of the authors are given: 1) the patient who developed hypoxic erythrocytosis against chronic pulmonary heart disease formed due to a combination of COPD and Pickwick syndrome and "sleep apnea"; 2) the patient admitted to hospital initially only in connection with changes in the blood (erythrocytosis) for differential diagnosis and who was revealed to have arteriovenous malformation of the lung vessels; 3) the case of primary pulmonary hypertension diagnosis in a young patient with multiple comorbidities.

KEYWORDS

hypoxic erythrocytosis, chronic myeloproliferative diseases, differential diagnosis.

1. Belokon´ N.A., Podzolkov V.P. Congenital heart defects. Moscow: Meditsina; 1991 (in Russian).

2. Voytsekhovskiy V.V., Landyshev Yu.S., Tseluyko S.S., Lysenko A.V. Leukemoid response and erythrocytoses. Blagoveshchensk: Zeya; 2013 (in Russian).

3. Voytsekhovskiy V.V., Gruzdova A.V., Filatova E.A., Goborov N.D., Makarova N.V., Sinyuk A.A., Kondrakhina A.P. The analysis of infectious complications of hemoblastosis in the Amur region. Bûlleten´ fiziologii i patologii dyhaniâ 2012; 46:64-68 (in Russian).

4. Vydyborets S.V. Symptomatic erythrocytosis: review. Vrachebnoe delo 1989; 12:31-35.

5. Mamaev N.N., Ryabov S.I., editors. Hematology. St. Petersburg: SpetsLit; 2011 (in Russian).

6. Rukavitsyn O.A., editor. Hematology. National guidelines. Moscow: GEOTAR-Меdia; 2015 (in Russian).

7. Grinshpun L.D., Pivnik A.V., editors. Geriatric Hematology. Vol.1,2. Moscow: Меdium; 2011-2012 (in Russian).

8. Demidova А.V. Analysis of the causes of diagnostic errors of erythremia. Modern approaches to differential diagnosis of erythremia and secondary erythrocytosis. Terapevticheskiy arkhiv 1984; 56(6):147-153 (in Russian).

9. Demidova А.V. Secondary erythrocytosis. Terapevticheskiy arkhiv 1985; 57(7):49-54 (in Russian).

10. Demidova А.V., Khoroshko N.D. Erythremia and erythrocytoses. In: Vorob´ev A.I., editor. Manual on Hematology. Vol.3. Moscow: N´yudiamed; 2002. pp.21-28 (in Russian).

11. Demidova А.V. Polycythemia Vera In: Volkova M.A., editor. Clinical Oncohematology. Moscow: Meditsina; 2007. рр.586-605 (in Russian).

12. Landyshev Yu.S., Lenshin A.V. Manual on Pulmonology. Blagoveshchensk: RIO; 2003 (in Russian).

13. Landysheva I.V., Grigorenko A.A., Landyshev Yu.S., Dubyaga E.V. Clinical and functional, metabolic and morphological features of the formation of chronic pulmonary heart disease in chronic obstructive bronchitis. Blagoveshchensk: Zeya; 2008 (in Russian).

14. Fedoseev G.B, Ignatov Yu.D. Syndromic diagnosis and basic pharmacotherapy of internal medicine. Vol.2. St. Petersburg: Nordmedizdat; 2004 (in Russian).

15. Chazova I.Е. Idiopathic (primary) pulmonary hypertension. In: Belenkov Yu.N., Oganov R.G., editors. Cardiology. National guidelines. Moscow: GEOTAR-Меdia; 2008. pp.940-955 (in Russian).

16. Chuchalin А.G., editor. Pulmonology. National guidelines. Мoscow: GEOTAR-Меdia; 2009 (in Russian).

17. Shiffman F.J. Blood Pathophysiology. Moscow: Binom; 2015 (in Russian).

18. Adamson J.W. Erythropoietin: in vitro and in vivo studies of the regulation of erythropoiesis. Schweiz. Med. Wochenschr. 1988; 118(42):1501-1506.

19. Agarwal M.B. Polycythemia. Indian Pract. 1984; 33(1):55-61.

20. Balcerzak S.P., Bromberg P.A. Secondary polycythemia. Semin. Hematol. 1975; 12(4):353-382.

21. Berlin N.J. Diagnosis and classification the polycythemias. Semin. Hematol. 1975; 12(4):339-351.

22. Coulier B. Detection of pulmonary arteriovenous malformations by multislice spiral CT angiography. JBR-BTR 2003; 86:28.

23. Erslev A.J. Caro J. Pathophysiology and classification of polycythaemia. Scand. J. Haematol. 1983; 31(4):287-292.

24. Hoffman, R., Benz, E. J., Shattil, S.J., Furie, B., Cohen H. J., Silberstein, L.E., McGlave Р. Hematology: basic principles and practice, 3rd edition. New York: Churchill Livingstone; 2000.

25. Khurshid I, Downie G. H. Pulmonary arteriovenous malformation. Postgrad. Med. J. 2002; 78(918):191-197.

26. Napier J.A.F., Janovska-Wieczorek A. Erythropoietin measurements in the differential diagnosis of polycythemia. Brit. J. Haematol. 1981; 48(3):393-401.

27. Orwoll E.S., Orwoll R.J. Hematologic abnormalities in patients with endocrine and metabolic disorders. Hematol. Oncol. Clin. North Am. 1987; 1(2):261-279.

28. Rodak B.F. Diagnostic hematology. Philadelphia: WB Saunders; 1995.

29. Streiff M.B., Smith B., Spivak J.L. The diagnosis and management of polycythemia vera in the era since the Polycythemia Vera Study Group: a survey of American Society of Hematology members’ practice patterns. Blood 2002; 99(4):1144-1149.

30. Vainchenker W., Constantinescu S.N. A unique activating mutation in JAK2 (V617F) at the origin of polycythemia vera and allows a new classification of myeloproliferative diseases. Hematology Am. Soc. Hematol. Educ. Program 2005: 195-200.

31. Wedzicha J.A., Cotes P.M., Empey D.W., Newland A.C., Royston J.P., Tam R.C. Serum immunoreactive erythropoietin in hypoxic lung disease with and without polycythaemia. Clin.Sci. (Lond.) 1985; 69(4):413-422.

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Editor-in-Chief, editorial board chair

GOST

Landyshev Y., Voytsekhovskiy V. V., Goborov N. D. HYPOXIC ERYTHROCYTOSIS // Bulletin physiology and pathology of respiration. 2016. no. 61. pp. 107-119. DOI: https://doi.org/10.12737/21462. (Date of access 07.10.2026).

MLA

Yuriy Landyshev, Voytsekhovskiy V. V., Goborov N. D.. "HYPOXIC ERYTHROCYTOSIS." Bulletin physiology and pathology of respiration 1.61 (2016): 107-119. DOI: https://doi.org/10.12737/21462.

APA

Landyshev Y., Voytsekhovskiy V. V., Goborov N. D. (2016). HYPOXIC ERYTHROCYTOSIS. Bulletin physiology and pathology of respiration, 1(61), 107-119. https://doi.org/10.12737/21462

Chicago

Yuriy Landyshev, Voytsekhovskiy V. V., Goborov N. D.. "HYPOXIC ERYTHROCYTOSIS." Bulletin physiology and pathology of respiration 1, no. 61 (2016): 107-119. https://doi.org/10.12737/21462.

WIKI

{{cite journal | author = Landyshev Y., Voytsekhovskiy V. V., Goborov N. D. | title = HYPOXIC ERYTHROCYTOSIS | journal = Bulletin physiology and pathology of respiration | year = 2016 | volume = 1 | issue = 61 | pages = 107-119 | doi = 10.12737/21462 }}

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