The Bank of Biological Samples by Seversk Biophysical Research Center

T. Takhauova; D. Isubakova; E. Bronikovskaya; O. Tsymbal; M. Khalyuzova; L. Takhauova; A. Karpov; N. Litviakov; I. Milto

doi:10.12737/1024-6177-2020-65-2-21-26

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THE BANK OF BIOLOGICAL SAMPLES BY SEVERSK BIOPHYSICAL RESEARCH CENTER The Bank of Biological Samples by Seversk Biophysical Research Center

АА Аа

Published in Medical Radiology and radiation safety · Volume 65, Issue 2 · Pages 21–26 · Rubric: Radiation epidemiology

DOI: https://doi.org/10.12737/1024-6177-2020-65-2-21-26

Received: 12.04.2020 Accepted: 26.07.2023

Authors

T. Takhauova

D. Isubakova

E. Bronikovskaya

O. Tsymbal

et al.

M. Khalyuzova

L. Takhauova

A. Karpov

N. Litviakov

I. Milto

T. Takhauova

Academic degree: doctor of medical sciences

Seversk Biophysical Research Center Director · Russian Federation · Seversk

Siberian State Medical University Professor · Russian Federation · Tomsk

D. Isubakova

Seversk Biophysical Research Center Junior Researcher · Russian Federation · Seversk

Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences Junior Researcher · Russian Federation · Seversk

E. Bronikovskaya

Seversk Biophysical Research Center Leading Researcher · Russian Federation · Seversk

O. Tsymbal

Seversk Biophysical Research Center Junior Researcher · Russian Federation · Seversk

M. Khalyuzova

Seversk Biophysical Research Center Researcher · Russian Federation · Seversk

L. Takhauova

Siberian State Medical University Russian Federation · Tomsk

A. Karpov

Academic degree: doctor of medical sciences

Seversk Biophysical Research Center Head of Department · Russian Federation · Seversk

Siberian State Medical University Professor · Russian Federation · Tomsk

N. Litviakov

Academic degree: doctor of sciences in biology

Seversk Biophysical Research Center Head of Laboratory · Russian Federation · Seversk

Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences Russian Federation · Tomsk

National Research Tomsk State University Russian Federation · Tomsk

I. Milto

Academic degree: doctor of sciences in biology

Science rang: docent

Seversk Biophysical Research Center Head of Department · Russian Federation · Seversk

Siberian State Medical University Associate Professor · Russian Federation · Tomsk

ABSTRACT

Purpose: Description of the collection, structure and development dynamics during the period from 2015 to 2019 of the biological material bank of the Seversk Biophysical Research Center, as well as research works carried out using biological material from its collection. Material and methods: The collection of bank of biological material includes the following types of biological material: venous blood, genomic DNA of white blood cells, cytogenetic suspensions of blood lymphocytes, surgical, biopsy and autopsy material. Biological material was obtained from people exposed to chronic radiation exposure: employees of the nuclear industry and the population permanently residing in the territory located in the area of the nuclear industry. Results: At present, the collection of the biological material bank contains more than 21,000 samples of biological material obtained from more than 8,000 donors. The collection of bank of biological material is represented by 4 main blocks: biological material of conditionally healthy employees of company of the nuclear industry (Siberian Chemical Combine); biological material of conditionally healthy people permanently residing in the territory located in the area of the nuclear industry enterprise (Seversk); biological material of patients (workers of the Siberian Chemical Combine and residents of Seversk) with malignant neoplasms and biological material of patients (workers of the Siberian Chemical Combine and residents of Seversk) with acute myocardial infarction. In the collection of bank of biological material, the proportion of samples of biological material of relatively healthy workers of the Siberian Chemical Combine is 33 %, residents of Seversk — 40.8 %, patients with malignant neoplasms — 22.2 %, patients with acute myocardial infarction — 4 %. Conclusion: Biological material bank Seversk Biophysical Research Center is unique collection of biological material samples of healthy people and patients with socially significant diseases. A feature of the biological material of the biological material bank is that it is obtained from people who have been exposed to chronic low-intensity radiation exposure and can be used to evaluate its radiogenic effects.

KEYWORDS

bank of biological material, ionizing radiation, chromosomal aberration, malignant neoplasms, acute myocardial infarction

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GOST

Takhauova T. M., Isubakova D. S., Bronikovskaya E. V., Tsymbal O. S., Khalyuzova M. V., Takhauova L. R., Karpov A. B., Litviakov N. V., Milto I. V. The Bank of Biological Samples by Seversk Biophysical Research Center // Medical Radiology and radiation safety. 2020. no. 2. pp. 21-26. DOI: https://doi.org/10.12737/1024-6177-2020-65-2-21-26. (Date of access 10.10.2026).

MLA

T. Takhauova, Isubakova D. S., Bronikovskaya E. V., Tsymbal O. S., Khalyuzova M. V., Takhauova L. R., Karpov A. B., Litviakov N. V., Milto I. V.. "The Bank of Biological Samples by Seversk Biophysical Research Center." Medical Radiology and radiation safety 65.2 (2020): 21-26. DOI: https://doi.org/10.12737/1024-6177-2020-65-2-21-26.

APA

Takhauova T. M., Isubakova D. S., Bronikovskaya E. V., Tsymbal O. S., Khalyuzova M. V., Takhauova L. R., Karpov A. B., Litviakov N. V., Milto I. V. (2020). The Bank of Biological Samples by Seversk Biophysical Research Center. Medical Radiology and radiation safety, 65(2), 21-26. https://doi.org/10.12737/1024-6177-2020-65-2-21-26

Chicago

T. Takhauova, Isubakova D. S., Bronikovskaya E. V., Tsymbal O. S., Khalyuzova M. V., Takhauova L. R., Karpov A. B., Litviakov N. V., Milto I. V.. "The Bank of Biological Samples by Seversk Biophysical Research Center." Medical Radiology and radiation safety 65, no. 2 (2020): 21-26. https://doi.org/10.12737/1024-6177-2020-65-2-21-26.

WIKI

{{cite journal | author = Takhauova T. M., Isubakova D. S., Bronikovskaya E. V., Tsymbal O. S., Khalyuzova M. V., Takhauova L. R., Karpov A. B., Litviakov N. V., Milto I. V. | title = The Bank of Biological Samples by Seversk Biophysical Research Center | journal = Medical Radiology and radiation safety | year = 2020 | volume = 65 | issue = 2 | pages = 21-26 | doi = 10.12737/1024-6177-2020-65-2-21-26 }}

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