Influence of Drinking Water Quality on the Current of Acute Radiation Disease in Mice

T. Bichkova; I. Andrianova; O. Nikitenko; N. Stavrakova; I. Parfenova; T. Karaulova; A. Gordeev; A. Ivanov

doi:10.12737/1024-6177-2021-66-6-34-38

UDC 61 CSCSTI 76.33 Russian Classification of Professions by Education 31.06.2001 Russian Library and Bibliographic Classification 534 Russian Trade and Bibliographic Classification 5712 CSCSTI 76.03 Russian Classification of Professions by Education 31.08.08 Russian Classification of Professions by Education 32.08.12 Russian Classification of Professions by Education 14.04.02 Russian Library and Bibliographic Classification 51 Russian Trade and Bibliographic Classification 5734 Russian Trade and Bibliographic Classification 6212 Russian Trade and Bibliographic Classification 5708

13 more Collapse

INFLUENCE OF DRINKING WATER QUALITY ON THE CURRENT OF ACUTE RADIATION DISEASE IN MICE Influence of Drinking Water Quality on the Current of Acute Radiation Disease in Mice

АА Аа

Published in Medical Radiology and radiation safety · Volume 66, Issue 6 · Pages 34–38 · Rubric: Radiation biology

DOI: https://doi.org/10.12737/1024-6177-2021-66-6-34-38

Received: 17.12.2021 Accepted: 24.03.2024

Authors

T. Bichkova

I. Andrianova

O. Nikitenko

N. Stavrakova

et al.

I. Parfenova

T. Karaulova

A. Gordeev

A. Ivanov

T. Bichkova

A.I. Burnasyan Federal Medical Biophysical Center of FMBA Junior Researcher · Russian Federation · Moscow

Institute of Biomedical Problems, Russian Academy of Sciences Junior Researcher · Russian Federation · Moscow

I. Andrianova

A.I. Burnasyan Federal Medical Biophysical Center of FMBA Russian Federation · Moscow

O. Nikitenko

A.I. Burnasyan Federal Medical Biophysical Center of FMBA Junior Researcher · Russian Federation · Moscow

Institute of Biomedical Problems, Russian Academy of Sciences Junior Researcher · Russian Federation · Moscow

N. Stavrakova

A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia Russian Federation

I. Parfenova

A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia Russian Federation

T. Karaulova

A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia Russian Federation

A. Gordeev

Academic degree: candidate of medical sciences

A.I. Burnasyan Federal Medical Biophysical Center of FMBA Head of Laboratory · Russian Federation · Moscow

A. Ivanov

Academic degree: doctor of medical sciences

Joint Institute for Nuclear Research Head of Laboratory · Russian Federation · Dubna

Institute for Biomedical Problems Russian Federation · Moscow

A.I. Burnasyan Federal Medical Biophysical Center (FMBC) FMBA Russian Federation · Moscow

ABSTRACT

Purpose: Assessing the role of various factors in the formation of radioresistance is an important branch of radiobiology. The quality of drinking water, as it turned out, can significantly affect radioresistance. Against the background of studying the antiradiation properties of various types of water, differing in mineral and isotopic composition, the problem of the influence of tap water on the course of radiation injury remained underestimated. This circumstance determined the purpose of the work: to evaluate the modifying effect of tap water on the course of acute radiation sickness after X-ray irradiation of mice at an average lethal dose. Material and methods: Female ICR (CD-1) mice were irradiated with an average lethal dose once – 6.5 Gy of X-ray irradiation. After irradiation, half of the mice received tap water as drinking water, and the other half received artificially mineralized drinking water. Results: Keeping animals on tap water significantly reduced the survival rate of mice both with a single dose (log-rank test p=0.02, χ2=5.38) compared with animals receiving artificially mineralized distilled water. In addition, in the group of mice that received tap water, an increase in the rate of death of mice and a lower preservation of the group mass of animals during the development of acute radiation injury was noted. Conclusion: Tap water, used as drinking water, increases the damaging effect of radiation when X-rays are irradiated in mice.

KEYWORDS

tap water, artificially mineralized distilled water, X-ray irradiation, survival rate, mortality rate, mice, model

1. Yagunov A.S., Reeves G.I., Tokalov S.V., Chukhlovin A.B., Afanassiev B.V. Animal Studies of Residual Hematopoietic and Immune System Injury from Low Dose/Low Dose Rate Radiation and Heavy Metals. Bethesda: MD: Armed Forces Radiobiology Research Institute, 1998. (AFFRI). DOIhttps://doi.org/10.13140/2.1.3584.0007.

2. Carpenter D.O., Bushkin-Bedient S. Exposure to Chemicals and Radiation During Childhood and Risk for Cancer Later in Life // J. Adolesc Health. 2013. V.52, No. 5. P. 21-29. doihttps://doi.org/10.1016/j.jadohealth.2013.01.027.

3. Vacek A., Sikulová J., Bartonícková A. Radiation Resistance in Mice Increased Following Chronic Application of Li2CO3 // Acta Radiol Oncol. 1982. V. 21. No. 5. P. 325-330. DOI:10.3109 /02841868209134023.

4. Chlorinated Drinking-Water; Chlorination by-Products; Some other Halogenated Compounds; Cobalt and Cobalt Compounds. International Agency for Research on Cancer (IARC) Working Group, Lyon, 12-19 June 1990 // IARC Monogr Eval Carcinog Risks Hum. 1991. No. 52. P. 45-399.

5. National Toxicology Program. NTP Toxicology and Carcinogenesis Studies of Chlorinated Water (CAS Nos. 7782-50-5 and 7681-52-9) and Chloraminated Water (CAS No. 10599-90-3) (Deionized and Charcoal-Filtered) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies) // Natl Toxicol Program Tech Rep Ser. 1992. No. 392. P. 1-466.

6. Sanitarno-epidemiologicheskie pravila i normativy SanPiN 2.1.4.1074-01 Pit'evaya voda. Gigienicheskie trebovaniya k kachestvu vody centralizovannyh sistem pit'evogo vodosnabzheniya. Kontrol' kachestva. Gigienicheskie trebovaniya k obespecheniyu bezopasnosti sistem goryachego vodosnabzheniya.

7. Kaplan E.L., Meier P. Non-Parametric Estimation from Incomplete Observations // J. Am. Stat. Assoc. 1958. V. 53, No. 282. P. 457-481.

8. Sacher G.A. On the Statistical Nature of Mortality, with Especial Reference to Chronic Radiation Mortality // Radiology. 1956. V.67, No. 2. P. 250-258. doi:https://doi.org/10.1148/67.2.250.

9. WHO Library Cataloging in publication data Guidelines for drinking water quality. WHO, 2011. P. 584.

10. Rahmanin Yu.A. Biofizika vody: kvantovaya nelokal'nost' v tehnologiyah vodopodgotovki, regulyatornaya rol' associirovannoy vody v kletochnom metabolizme, normirovanie bioenergeticheskoy aktivnosti pit'evoy vody / Pod red. Rahmanina Yu.A., Stehina A.A., Yakovlevoy G.V. M.: URSS, 2016. 346 s.

11. Ivanov A.A., Andrianova I.E., Mal'cev V.N., Shal'nova G.A., Stavrakova N.M., Bulynina T.M., Dorozhkina O.V., Karaulova T.A., Gordeev A.V., Bushmanov A.Yu. Vliyanie pit'evoy vody razlichnogo kachestva na intaktnyh i obluchennyh myshey // Gigiena i sanitariya. 2017. № 9. S. 854-860. DOIhttps://doi.org/10.18821/0016-9900-2017-96-9-854-860.

12. Laissue J.A., Altermatt H.J., Bally E., Gebbers J.O. Protection of Mice from Whole Body Gamma Irradiation by Deuteration of Drinking Water: Hematologic Findings // Exp. Hematol. 1987. V.15, No. 2. P.177-180.

13. Ivanov A.A., Ushakov I.B., Kulikova E.I., Kryuchkova D.M., Severyuhin Yu.S., Vorozhcova S.V., Abrosimova A.N., Gaevskiy V.A., Sinyak Yu.E., Grigor'ev A.I. Legkoizotopnaya voda - sredstvo lecheniya ostroy luchevoy bolezni // Aviakosmicheskaya i ekologicheskaya medicina. 2013. T. 47, № 5. S. 40-44.

14. Abrosimova A.N., Rakov D.V., Sinyak Yu.E. Vliyanie «legkoy vody» na razvitie pomutneniya hrustalika u myshey posle mnogokratnogo γ-oblucheniya v nizkih dozah // Aviakosmicheskaya i ekologicheskaya medicina. 2009. T. 43, № 2, S. 29-32

15. Kulikova E.I., Kryuchkova D.M., Severyuhin Yu.S., Gaevskiy V.N., Ivanov A.A. Radiomodificiruyuschie svoystva vody s ponizhennym soderzhaniem deyteriya i tyazhelyh izotopov kisloroda // Aviakosmicheskaya i ekologicheskaya medicina. 2012. T. 46. № 6. S. 45-50.

16. Kryuchkova D.M., Andrianova I.E., Kovalenko M.A. i dr. Vliyanie mineraloorganicheskogo kompleksa na radiorezistentnost' myshey // Aviakosmicheskaya i ekologicheskaya medicina. 2013. T. 47. № 5. S. 37-40.

17. Cantor K.P., Hoover R., Hartge P., et al. Bladder Cancer, Drinking Water Source, and Tap Water Consumption: a Case-Control Study // J. Natl. Cancer Inst. 1987. V. 79. No. 6. P.1269-1279.

18. Ishidate M.Jr., Sofuni T., Yoshikawa K., Hayashi M., et al. Primary Mutagenicity Screening of Food Additives Currently Used in Japan // Food and Chemical Toxicology 1984. V.22, No. 8. P. 623-636. doi.org/10.1016/0278-6915(84)90271-0.

19. Eltahawy N.A., Sarhan O.M., Hammad A.S., et al. Effects of Combined Exposure to Aluminum Chloride and γ-Radiation on Histological and Ultrastructure of Intestinal Paneth Cells // Radiat. Res. Appl. Sci. 2016. No. 9. P. 400-408. doi.org/10.1016/j.jrras.2016.05.007.

JATS XML

Scientific and Production Editor

Boris Narkevich

medradiol@yandex.ru

561

downloads

GOST

Bichkova T. M., Andrianova I. E., Nikitenko O. V., Stavrakova N. M., Parfenova I. M., Karaulova T. A., Gordeev A. V., Ivanov A. A. Influence of Drinking Water Quality on the Current of Acute Radiation Disease in Mice // Medical Radiology and radiation safety. 2021. no. 6. pp. 34-38. DOI: https://doi.org/10.12737/1024-6177-2021-66-6-34-38. (Date of access 09.10.2026).

MLA

T. Bichkova, Andrianova I. E., Nikitenko O. V., Stavrakova N. M., Parfenova I. M., Karaulova T. A., Gordeev A. V., Ivanov A. A.. "Influence of Drinking Water Quality on the Current of Acute Radiation Disease in Mice." Medical Radiology and radiation safety 66.6 (2021): 34-38. DOI: https://doi.org/10.12737/1024-6177-2021-66-6-34-38.

APA

Bichkova T. M., Andrianova I. E., Nikitenko O. V., Stavrakova N. M., Parfenova I. M., Karaulova T. A., Gordeev A. V., Ivanov A. A. (2021). Influence of Drinking Water Quality on the Current of Acute Radiation Disease in Mice. Medical Radiology and radiation safety, 66(6), 34-38. https://doi.org/10.12737/1024-6177-2021-66-6-34-38

Chicago

T. Bichkova, Andrianova I. E., Nikitenko O. V., Stavrakova N. M., Parfenova I. M., Karaulova T. A., Gordeev A. V., Ivanov A. A.. "Influence of Drinking Water Quality on the Current of Acute Radiation Disease in Mice." Medical Radiology and radiation safety 66, no. 6 (2021): 34-38. https://doi.org/10.12737/1024-6177-2021-66-6-34-38.

WIKI

{{cite journal | author = Bichkova T. M., Andrianova I. E., Nikitenko O. V., Stavrakova N. M., Parfenova I. M., Karaulova T. A., Gordeev A. V., Ivanov A. A. | title = Influence of Drinking Water Quality on the Current of Acute Radiation Disease in Mice | journal = Medical Radiology and radiation safety | year = 2021 | volume = 66 | issue = 6 | pages = 34-38 | doi = 10.12737/1024-6177-2021-66-6-34-38 }}

Copy

Export: BibTeX EndNote RefMan RusMARC

INFLUENCE OF DRINKING WATER QUALITY ON THE CURRENT OF ACUTE RADIATION DISEASE IN MICE Influence of Drinking Water Quality on the Current of Acute Radiation Disease in Mice

Confirmation