АНАЛИЗ ЭФФЕКТИВНОСТИ ПРИМЕНЕНИЯ КЛЕТОЧНОЙ ТЕРАПИИ ПРИ ЛЕЧЕНИИ МЕСТНЫХ ЛУЧЕВЫХ ПОРАЖЕНИЙ
Рубрики: ОБЗОР
Аннотация и ключевые слова
Аннотация (русский):
С каждым годом удельный вес лучевой терапии как самостоятельного метода радикального лечения онкологических пациентов увеличивается. Воздействие радиационного облучения в результате лучевой терапии может приводить к развитию у пациентов местных лучевых поражений (МЛП) на коже и окружающих тканях. На сегодняшний день не существует стандартного метода лечения МЛП, известные методы малоэффективны. В связи с этим актуальными являются исследования, направленные на поиск эффективных методов лечения, приводящих к ускорению заживления ран, уменьшению процессов воспаления и снижению фиброза. В последние годы ведется активное изучение эффективности применения клеточной терапии, включая мезенхимальные стволовые клетки (МСК), их клеточные продукты, минимально-манипулированные клеточные продукты и др., в комплексной терапии МЛП. В представленном литературном обзоре рассмотрена эффективность применения клеточных продуктов при местных лучевых поражениях кожи, вызванных источниками ионизирующего излучения. Библиографический поиск работ проводился на базе портала PubMed, опубликованных в период с 2015 по август 2020 года.

Ключевые слова:
мезенхимальные стволовые клетки, стволовые клетки, местные лучевые поражения, лучевые язвы, ионизирующее излучение
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