г. Москва и Московская область, Россия
г. Москва и Московская область, Россия
г. Москва и Московская область, Россия
г. Москва и Московская область, Россия
ГРНТИ 76.33 Гигиена и эпидемиология
ГРНТИ 76.03 Медико-биологические дисциплины
ОКСО 31.06.2001 Клиническая медицина
ОКСО 31.08.08 Радиология
ОКСО 32.08.12 Эпидемиология
ОКСО 14.04.02 Ядерные физика и технологии
ББК 534 Общая диагностика
ББК 51 Социальная гигиена и организация здравоохранения. Гигиена. Эпидемиология
ТБК 5712 Медицинская биология. Гистология
ТБК 5734 Медицинская радиология и рентгенология
ТБК 6212 Радиоактивные элементы и изотопы. Радиохимия
ТБК 5708 Гигиена и санитария. Эпидемиология. Медицинская экология
Колоректальный рак (КРР) занимает лидирующие позиции по частоте заболеваемости и смертности во всем мире. Диссеминированный КРР при первичной диагностике составляет от 15 до 35 %. Метастазы в легких являются самым частым внебрюшным проявлением метастатического процесса. Доля больных, у которых выявлены изолированные метастазы в легких, составляет всего лишь от 2 до 7,4 %. Такие пациенты являются относительно редкими, и до настоящего времени нет четких рекомендаций по их лечебной тактике. Данное клиническое наблюдение описывает успешный случай применения предоперационной пролонгированной химиолучевой терапии на первичную опухоль и стереотаксическое облучение метастатических очагов в легких, с курсами лекарственной терапии, с дальнейшим оперативным вмешательством в радикальном объеме лапароскопическим доступом, у пациента с диссеминированным первично-множественным раком прямой кишки, синхронным раком сигмовидной кишки и 2 метастатическими очагами в обоих легких.
рак прямой кишки, диссеминированный, метастазы в легкие, стереотаксическая лучевая терапия, химиолучевая терапия
1. Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J, Rosso S. et al. Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012; Eur J Cancer 2013;49(6):1374-403.
2. Goldberg RM. Advances in the treatment of metastatic colorectal cancer. Oncologist. 2005; 10 Suppl 3:40-8.
3. Zacharakis M, Xynos I.D, Lazaris A. et al. Predictors of survival in stage IV metastatic colorectal cancer. Anticancer Res. 2010;30(2):653-60.
4. Manfredi S, Lepage C, Hatem C, Coatmeur O. et al. Epidemiology and management of liver metastases from colorectal cancer. Ann Surg. 2006;244(2):254-9.
5. Nordholm-Carstensen A, Krarup PM, Jorgensen LN, Wille-Jorgensen PA, et al. On behalf of Danish colorectal Cancer group. Occurrence and survival of synchronous pulmonary metastases in colorectal cancer: a nationwide cohort study. Eur J Cancer. 2014; 50:447-56.
6. Mitry E, Guiu B, Cosconea S, Jooste V, et al. Epidemiology, management and prognosis of colorectal cancer with lung metastases: a 30-year population-based study. Gut. 2010; 59(10):1383-8.
7. Tan KK, Lopes Gde L. Jr, Sim R, et al. How uncommon are isolated lung metastases in colorectal cancer? A review from database of 754 patients over 4 years. J Gastrointest Surg. 2009; 13:642- 648.
8. Clark JW, Grothey A. Systemic chemotherapy for nonoperable metastatic colorectal cancer: treatment recommendations. https://www.uptodate.com/contents/systemic-chemotherapy-for-nonoperable-metastatic-colorectal-cancer-treatment-recommendations ?search=systemic-chemotherapy-for-nonoperable-metastatic-colorectal-cancer-treatment& source=search_result&selected Title=1~150&usage_type= default&display_rank=1 (This topic last updated: Jan 13, 2020).
9. Blalock A. Recent advances in surgery. N Engl J Med. 1944;231:261-7.
10. Pfannschmidt J, Dienemann H, Hoffmann H. Surgical resection of pulmonary metastases from colorectal cancer: a systematic review of published series. Ann Thorac Surg. 2007; 84:324-38.
11. Pastorino U, Buyse M, Friedel G, et al. Long-term results of lung metastasectomy: prognostic analyses based on 5206 cases. J Thorac Cardiovasc Surg. 1997; 113:37-49.
12. Timmerman RD, Bizekis CS, Pass HI, et al. Local surgical, ablative, and radiation treatment of metastases. CA Cancer J Clin. 2009;59 P145-70.
13. Gonzalez M, Ris H.B, Krueger T, Gervaz P. Colorectal cancer and thoracic surgeons: close encounters of the third kind. Expert RevAnticancer Ther. 2012;12:495-503.
14. Treasure T. Pulmonary metastasectomy for colorectal cancer: weak evidence and no randomised trials. Eur J Cardiothorac Surg. 2008;33P300-2.
15. Inoue M, Kotake Y, Nakagawa K, Fujiwara K, et al. Surgery for pulmonary metastases from colorectal carcinoma. Ann Thorac Surg. 2000;70:380-3.
16. McAfee MK, Allen MS, Trastek VF, Ilstrup DM, et al. Colorectal lung metastases: results of surgical excision. Ann Thorac Surg. 1992; 53:780-5.
17. Regnard JF, Grunenwald D, Spaggiari L, et al. Surgical treatment of hepatic and pulmonary metastases from colorectal cancers. Ann Thorac Surg. 1998; 66:214-8.
18. Sakamoto T, Tsubota N, Iwanaga K, Yuki T, et al:ulmonary resection for metastases from colorectal cancer. Chest. 2001; 119:1069-72.
19. Carballo M, Maish M.S, Jaroszewski D.E, Holmes C.E. Videoassisted thoracic surgery (VATS) as a safe alternative for the resection of pulmonary metastases: a retrospective cohort study. J Cardiothorac Surg. 2009; 4:13.
20. Chao YK, Chang HC, Wu YC, Liu Y.H, et al. Management of lung metastases from colorectal cancer: video-assisted thoracoscopic surgery versus thoracotomy-a casematched study. Thorac Cardiovasc Surg. 2012; 60:398-404.
21. Dong S, Zhang L, Li W, Du J, et al. Evaluation of videoassisted thoracoscopic surgery for pulmonary metastases: a metaanalysis. PLoS ONE. 2014; 9:329.
22. Nakajima J, Murakawa T, Fukami T, Takamoto S. Is thoracoscopic surgery justified to treat pulmonary metastasis from colorectal cancer?. Interact Cardiovasc Thorac Surg. 2008; 7:212-6.
23. Nakas A, Klimatsidas M.N, Entwisle J, Martin-Ucar A.E, et al. Video-assisted versus open pulmonary metastasectomy: the surgeon’s finger or the radiologist’s eye?. Eur J Cardiothorac Surg. 2009; 36:469-74
24. Ibrahim T, Tselikas L, Yazbeck C, Kattan J. Systemic versus local therapies for colorectal cancer pulmonary metastasis: what to choose and when?. J Gastrointest Cancer 2016; 47:223-31.
25. Van Cutsem E, Cervantes A, Adam R, et al. ESMO consensus guidelines for the management of patients with metastatic colorectal cancer. Ann Oncol 2016; 27:1386-422.
26. Hiraki T, Gobara H, Iguchi T, Fujiwara H, et al. Radiofrequency ablation as treatment for pulmonary metastasis of colorectal cancer. World J Gastroenterol. 2014; 20:988-96.
27. Legras A, Mordant P, Cazes A, Riquet M.. Radiofrequency of lung metastases: should initial pneumothorax predict treatment failure?. Rev Pneumol Clin. 2013; 69:336-9.
28. Matsui Y, Hiraki T, Gobara H, et al. Long-term survival following percutaneous radiofrequency ablation of colorectal lungmetastases. J Vasc Interv Radiol. 2015; 26:303-10.
29. Schneider T. Thermal ablation of malignant lung tumours. Zentralbl Chir. 2015;140:104-8.
30. Takahashi W, Nakajima M, Yamamoto N, et al. Carbon ion radiotherapy for oligo-recurrent lung metastases from colorectal cancer: a feasibility study. Radiat Oncol. 2014;9:68.
31. Yan TD, King J, Sjarif A, Glenn D, et al. Learning curve for percutaneous radiofrequency ablation of pulmonary metastases from colorectal carcinoma: a prospective study of 70 consecutive cases. Ann Surg Oncol. 2006;13:1588-95.
32. Yan TD, King J, Sjarif A, Glenn D, et al. Percutaneous radiofrequency ablation of pulmonary metastases from colorectal carcinoma: prognostic determinants for survival. Ann Surg Oncol. 2006; 13:1529-37.
33. Nahum Goldberg S, Dupuy D.E. Image-guided radiofrequency tumor ablation: challenges and opportunities-part I. J Vasc Interv Radiol. 2001;12:1021-32.
34. Hiraki T, Gobara H, Mimura H, et al. Radiofrequency ablation of lung cancer at Okayama University Hospital: a review of 10 years of experience. Acta Med Okayama. 2011; 65:287-97.
35. de Baere T, Tselikas L, Pearson E, et al. Interventional oncology for liver and lung metastases from colorectal cancer: the current state of the art. Diagn Interv Imaging. 2015;96:647-54.
36. Ferguson J, Alzahrani N, Zhao J, Glenn D, et al. Long term results of RFA to lung metastases from colorectal cancer in 157 patients. Eur J Surg Oncol. 2015;41:690-5
37. Chi A, Liao Z, Nguyen NP, Xu J, et al. Systemic review of the patterns of failure following stereotactic body radiation therapy in early-stage non-small-cell lung cancer: clinical implications. Radiother Oncol. 2010;94:1-11
38. Fuks Z, Kolesnick R. Engaging the vascular component of the tumor response. Cancer Cell. 2005;8:89-91
39. Carvajal C, Navarro-Martin A, Cacicedo J, Ramos R, et al. Stereotactic body radiotherapy for colorectal lung oligometastases: preliminary single institution results. J BUON. 2015;20:158-65.
40. Filippi AR, Badellino S, Ceccarelli M, et al. Stereotactic ablative radiation therapy as first local therapy for lung oligometastases from colorectal cancer: a single-institution cohort study. Int J Radiat Oncol Biol Phys. 2015;91:524-9
41. Takeda A, Sanuki N, Kunieda E. Role of stereotactic body radiotherapy for oligometastasis from colorectal cancer. World J Gastroenterol. 2014;20:4220-9
42. Rusthoven KE, Kavanagh BD, Burri SH, et al. Multiinstitutional phase I/II trial of stereotactic body radiation therapy for lung metastases. J Clin Oncol. 2009;27:1579-84
43. Widder J, Klinkenberg TJ, Ubbels JF, Wiegman E.M, et al. Pulmonary oligometastases: metastasectomy or stereotactic ablative radiotherapy?. Radiother Oncol. 2013;107:409-13
44. Schlijper RC, Grutters JP, Houben R, et al. What to choose as radical local treatment for lung metastases from colo-rectal cancer: surgery or radiofrequency ablation?. Cancer Treat Rev. 2014;40:60-7.
